Provides an introduction to the field of bioinformatics from a statistical point of view. Students will be taught how to apply appropriate statistical methods to the analysis of Bioinformatic data. The course is offered in conjunction with the Biostatistics Collaboration of Australia (BCA)
|Faculty||Faculty of Health and Medicine|
|School||School of Medicine and Public Health|
Semester 2 - 2014
(Distance Education - Callaghan)
Previously offered in 2012
On completion students will: i) Explain the core dogma of molecular biology and the central ideas of population genetics ii) Access appropriate web based sources for data, and download the data in suitable format, when given a problem which requires genome or proteome data for its solution. iii) Understand and apply core bioinformatics techniques for the analysis of DNA and protein sequence data, such as global sequence alignment, BLAST, Hidden Markov Models, evolutionary models and phylogenetic tree fitting. iv) Process large quantities of data (such as the expression profiles of thousands of genes resulting from microarray experiments) using R, and communicate results in language suitable for presentation to both a bioinformatics journal and a lay audience.
The first component of the course is an introduction to various topics of elementary molecular biology and population genetics. Conducting database searches (of DNA, RNA, amino acids and proteins databases) is one of the most common tasks in bioinformatics, so a grounding in these methods is provided.
|Replacing Course(s)||This course will replace the existing BCA course BIOS6110 (Bioinformatics and Statistical Genetics)|
|Assumed Knowledge||Data Management and Statistical Computing (BIOS6010); Mathematical Background for Biostatistics (BIOS6040); Principles of Statistical Inference (BIOS6050); Linear Models (BIOS6070); Probability and Distribution Theory (BIOS6170).|
|Modes of Delivery||Distance Learning : Paper Based
|Teaching Methods||Self Directed Learning|
|Compulsory Components||None listed|
|Course Materials||None listed|
|Timetable||2014 Course Timetables for BIOS6111|