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PHAR6113

Pharmacokinetics

10 Units

Develops the students understanding of the processes involved in drug absorption, distribution and elimination and the way in which these processes influence the design of dosage regimens for individual patients.

Faculty Faculty of Health and Medicine
School School of Biomedical Sciences and Pharmacy
Availability

Not currently offered

Objectives

At the end of the course, students should:

  1. Describe the role of pharmacodynamic and pharmacokinetic factors as determinants of drug response.
  2. Calculate pharmacokinetic parameters and understand their physiological determinants.
  3. Describe the role of physiologic, pathologic and pharmacological factors on a drug’s pharmacokinetics.
  4. Calculate dosage regimens for young and elderly patients with disease states or interacting drugs
  5. Understand the biopharmaceutical factors which influence invivo performance of dosage forms and the methods of evaluation.
Content
  1. General principles of drug action and receptor theory
  2. Concept of primary and secondary pharmacokinetic parameters-clearance, volume of distribution and half life and their calculation
  3. Pharmacokinetic processes of drug absorption, distribution and elimination and their physiological determinants-blood flow, binding and intrinsic clearance
  4. Non-linear pharmacokinetics
  5. Dosage adjustment in patients with disease states, the young and the elderly
  6. Biopharmaceutics and Bioequivalence
  7. Generic drug products and brand substitution
  8. Population Pharmacokinetics
  9. Introduction to clinical pharmacokinetics
Replacing Course(s) Replacing PHAR6002 Pharmacokinetics 10 Units
Transition Students requiring to repeat PHAR6002 Pharmacokinetics will undertake PHAR6113 Pharmacokinetics
Industrial Experience 0
Assumed Knowledge Entry level requirements for Master of Pharmacy
Modes of Delivery Internal Mode
Teaching Methods Lecture
Tutorial
Computer Lab
Assessment Items
  • Examination: Class - In class examination during trimester
  • Essays / Written Assignments - Problem sets and tutorial worksheets.
  • Examination: Formal - Examination at the end of trimester. May comprise True/False, multiple choice and short answer questions and calculations.
  • Other: (please specify) - Students must achieve a passing grade overall to obtain a passing or higher grade in this course. Students must demonstrate competency in the theoretical knowledge that forms part of the core competencies required of a pharmacist
Contact Hours
  • Lecture: for 2 hour(s) per Week for 12 weeks
  • Computer Lab: for 2 hour(s) per Week for 10 weeks
  • Tutorial: for 2 hour(s) per Week for 1 weeks
Compulsory Components
  • Requisite by Enrolment: This course is available to students enrolled in the Master of Pharmacy program.
Course Materials None listed
Timetable 2014 Course Timetables for PHAR6113

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