PHAR6113

Pharmacokinetics

10 Units

Develops the students understanding of the processes involved in drug absorption, distribution and elimination and the way in which these processes influence the design of dosage regimens for individual patients.

Faculty Faculty of Health and Medicine
School School of Biomedical Sciences and Pharmacy
Availability Trimester 1 - 2015 (Callaghan Campus)
Learning Outcomes

On successful completion of this course, students will be able to:

  1. Describe the role of pharmacodynamic and pharmacokinetic factors as determinants of drug response.
  2. Calculate pharmacokinetic parameters and understand their physiological determinants.
  3. Describe the role of physiologic, pathologic and pharmacological factors on a drug’s pharmacokinetics.
  4. Calculate dosage regimens for young and elderly patients with disease states or interacting drugs
  5. Understand the biopharmaceutical factors which influence invivo performance of dosage forms and the methods of evaluation.
Content
  1. General principles of drug action and receptor theory
  2. Concept of primary and secondary pharmacokinetic parameters-clearance, volume of distribution and half life and their calculation
  3. Pharmacokinetic processes of drug absorption, distribution and elimination and their physiological determinants-blood flow, binding and intrinsic clearance
  4. Non-linear pharmacokinetics
  5. Dosage adjustment in patients with disease states, the young and the elderly
  6. Biopharmaceutics and Bioequivalence
  7. Generic drug products and brand substitution
  8. Population Pharmacokinetics
  9. Introduction to clinical pharmacokinetics
Assumed Knowledge Entry level requirements for Master of Pharmacy
Assessment Items
  • In Term Test: Written Examination/Assignment
  • Formal Examination: Formal Exam
Contact Hours
  • Computer Lab: for 2 hour(s) per Week for Weeks
  • Lecture: for 2 hour(s) per Week for Weeks
  • Tutorial: for 2 hour(s) per Week for Weeks (In week 1 a 3hr program introduction will be scheduled and a class examination will also be scheduled during trimester.)
Timetable 2015 Course Timetables for PHAR6113

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