PHAR6123

Human Genomics and Biomolecular Analysis for Pharmacy

10 Units

Represents a blend between fundamental concepts and current issues in molecular medicine. Focuses on the relationships between structure, function and analysis of proteins and nucleic acids as applied to human disease and provides an introduction to modern concepts of genomic structure, function and analysis arising from the Human Genome project.

Faculty Faculty of Health and Medicine
School School of Biomedical Sciences and Pharmacy
Availability Trimester 2 - 2014 (Callaghan Campus)
Trimester 2 - 2015 (Callaghan Campus)
Objectives

At the end of the course, students should have an understanding of:

  1. the nature of biopharmaceuticals and the role of biomolecular technologies in their development and application
  2. structural features of proteins and nucleic acids;
  3. the inter-relationship between molecular structure and molecular function, and its relevance to therapeutics applications
  4. the importance of molecular structure as it applies to fundamental biomedical analytical techniques;
  5. new and emerging biopharmaceuticals and targets
  6. human genomic structure, function and analysis;
  7. basic Mendelian genetics;
  8. basic population genetics
Content
  1. Introduction to biopharmaceuticals
  2. Protein structure/function and handling
  3. Nucleic acid structure/function
  4. Gene manipulation and recombinant DNA technology
  5. Sources of biopharmaceuticals (expression systems)
  6. Downstream processing (recovery, purification and quantitation of proteins)
  7. Cell signaling
  8. Nucleic acid and cell-based therapeutics
  9. Identification of new targets
  10. Human Genome and Inheritance
  11. Genomic Abnormalities
  12. Genetic testing
  13. Human Genome Project
  14. Population Genetics
  15. Pharmacogenomics.
Replacing Course(s) Replacing PHAR6015 Human Genomics and Biomolecular Analysis for Pharmacy. 10 Units
Transition NA
Industrial Experience 0
Assumed Knowledge Entry level requirements for Master of Pharmacy
Modes of Delivery Internal Mode
Teaching Methods Problem Based Learning
Lecture
Integrated Learning
Self Directed Learning
Tutorial
Computer Lab
Assessment Items
  • Examination: Class - Mid trimester Course learning objectives 1-4
  • Examination: Formal - End of trimester Course learning objectives 5-8
  • Other: (please specify) - Problem based learning report Course learning objectives 1-5 Genetics Assessment Course learning objectives 6-8
  • Other: (please specify) - Compulsory Course Component: Students must demonstrate competency in the theoretical knowledge that forms part of the core competencies required of a pharmacist. To do this students must show they are competent in all objectives by achieving a passing grade in the combined mid trimester and formal examination, and overall to be able to obtain a passing or higher grade in this course.
Contact Hours
  • Lecture: for 2 hour(s) per Week for 12 weeks
  • Tutorial: for 1 hour(s) per Week for 1 weeks
  • Tutorial: for 2 hour(s) per Week for 8 weeks
  • Computer Lab: for 2 hour(s) per Week for 4 weeks
Compulsory Components
  • Requisite by Enrolment: This course is only available to students enrolled in the Master of Pharmacy program
  • Compulsory Course Component: The assessment components test a student's competency in one or more of the course learning objectives since these form part of the core competencies required of a pharmacist so students must: 1. achieve a passing grade in the combined mid trimester and formal examination.
Course Materials None listed
Timetable 2015 Course Timetables for PHAR6123

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