PHAR6123

Human Genomics and Biomolecular Analysis for Pharmacy

10 Units

Represents a blend between fundamental concepts and current issues in molecular medicine. Focuses on the relationships between structure, function and analysis of proteins and nucleic acids as applied to human disease and provides an introduction to modern concepts of genomic structure, function and analysis arising from the Human Genome project.

Faculty Faculty of Health and Medicine
School School of Biomedical Sciences and Pharmacy
Availability Trimester 2 - 2015 (Callaghan Campus)
Learning Outcomes

On successful completion of this course, students will be able to:

  1. The nature of biopharmaceuticals and the role of biomolecular technologies in their development and application
  2. Structural features of proteins and nucleic acids;
  3. The inter-relationship between molecular structure and molecular function, and its relevance to therapeutics applications
  4. The importance of molecular structure as it applies to fundamental biomedical analytical techniques;
  5. New and emerging biopharmaceuticals and targets
  6. Human genomic structure, function and analysis;
  7. Basic Mendelian genetics;
  8. Basic population genetics
Content
  1. Introduction to biopharmaceuticals
  2. Protein structure/function and handling
  3. Nucleic acid structure/function
  4. Gene manipulation and recombinant DNA technology
  5. Sources of biopharmaceuticals (expression systems)
  6. Downstream processing (recovery, purification and quantitation of proteins)
  7. Cell signaling
  8. Nucleic acid and cell-based therapeutics
  9. Identification of new targets
  10. Human Genome and Inheritance
  11. Genomic Abnormalities
  12. Genetic testing
  13. Human Genome Project
  14. Population Genetics
  15. Pharmacogenomics.
Assumed Knowledge Entry level requirements for Master of Pharmacy
Assessment Items
  • Formal Examination: Examination - mid and end of trimester *
  • Presentation: Problem based learning oral presentation
  • Report: Genetics assessment
Contact Hours
  • Computer Lab: for 2 hour(s) per Week for Weeks
  • Lecture: for 2 hour(s) per Week for Weeks
  • Tutorial: for 17 hour(s) per Term (2 hours per week for 8 weeks and 1 hours per week for 1 week)
Requisites
  • Course Assessment Requirements:: 1. Formal Examination: Pass Requirement - Students must pass this assessment item to pass the course.
Timetable 2015 Course Timetables for PHAR6123

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